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Broad Institute

Google DeepMind Launches AlphaGenome Atlas, Mapping 9 Billion DNA Variants

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Google DeepMind Launches AlphaGenome Atlas, Mapping 9 Billion DNA Variants

Kansas City, Mo. – September 12, 2026 -- Google DeepMind has released AlphaGenome Atlas, a one-petabyte AI resource containing molecular-effect predictions for more than 9 billion possible single-letter DNA changes across the human genome, giving researchers browser-based access to the largest catalogue of its kind without writing code.

Atlas condenses billions of genetic variants into a single searchable score

The human genome's approximately 3 billion DNA letters create over 9 billion possible single-letter substitutions, a scale impossible to test experimentally in a lab. AlphaGenome Atlas assigns each variant thousands of molecular-effect predictions across hundreds of human cell types and tissues, feeding into a new AlphaGenome Variant Impact (AVI) score that combines AlphaGenome, AlphaMissense and evolutionary conservation data to rank variants across both protein-coding and non-coding regions.