LUNGevity, RETpositive Award $340,000 to Fight RET Cancer Resistance
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WASHINGTON – October 29, 2026 -- LUNGevity Foundation and patient advocacy group RETpositive have awarded a combined $340,000 to two research projects targeting drug resistance in RET-positive cancers, where tumors eventually outlast the two FDA-approved RET tyrosine kinase inhibitors (TKIs).
RET fusions drive 1% to 2% of non-small cell lung cancers
RET fusions occur when part of the RET gene joins with another gene. Beyond lung cancer, RET alterations appear in thyroid, colon and breast cancers. Both approved TKIs can be effective, but tumors evolve resistance and resume growth, which the organizations name as the critical priority for patients.