AstraZeneca

Washington – October 16, 2026 -- Nearly half of patients with hormone receptor positive, HER2 negative advanced breast cancer develop resistance to first-line endocrine therapy driven by the ESR1 mutation (ESR1m), according to a new Academy of Managed Care Pharmacy (AMCP) Market Insights Program report. The report finds that biomarker testing and treatment paradigms are evolving faster than the evidence payers need to manage them.

Testing uncertainty drives inconsistent practice and coverage friction

Patients with ESR1m stay on ineffective treatment until radiologic progression is detected. Monitoring for the mutation with circulating tumor DNA (ctDNA) liquid biopsy before progression can enable an early switch to effective therapy and extend time on first-line treatment.

Sydney – October 12, 2026 -- The Safety Review Committee (SRC) for Racura Oncology's HARNESS-1 trial has cleared lead drug RC220 to escalate to 100 mg/m2, after finding no dose-limiting toxicities in either Cohort 1 patient. The Phase 1a/b study combines RC220 with osimertinib in patients with EGFR-mutant non-small cell lung cancer (NSCLC).

Both Cohort 1 patients received RC220 at 50 mg/m2 by intravenous infusion alongside osimertinib at 80 mg daily. The second patient has received three RC220 doses, given 21 days apart, with no dose-limiting toxicities or treatment-related safety concerns.

Holon, Israel – October 6, 2026 -- Compugen Ltd. (NASDAQ: CGEN; TASE: CGEN) will join a fireside chat at the H.C. Wainwright 3rd Annual AI Based Drug Discovery & Development Conference, a virtual event running October 8-9, 2026.

Management confirms October 8 session with live investor webcast

The fireside chat is scheduled for Thursday, October 8, 2026, at 9:30 AM ET. A live webcast will stream via the Investor Relations events page on Compugen's website, with a replay available afterward.

North Bethesda, Md. – September 24, 2026 -- The International Society for Pharmaceutical Engineering (ISPE) will convene its 2026 Annual Meeting & Expo in Washington, D.C. from October 18-21, drawing pharmaceutical manufacturing leaders for four days of hybrid sessions combining in-person and virtual attendance.

Lonza and Eli Lilly executives headline keynote lineup on manufacturing innovation

Wolfgang Wienand, PhD, CEO of Lonza, will present "The Lonza Engine: Manufacturing the Medicines of Tomorrow," while Kevin Trivett, Senior Vice President of Device and Packaging Operations Manufacturing at Eli Lilly and Company, delivers "Lilly: Embracing Technology to Reach Patients." Additional featured speakers include Marla Phillips, PhD, CEO and President of Pathway for Patient Health LLC, addressing AI and human oversight in manufacturing loops, and cancer survivor and research advocate Jamie Valvano.

Pune, India – September 22, 2026 -- The global lupus nephritis market was valued at $1.96 billion in 2025 and is projected to reach $4.08 billion by 2034, expanding at a compound annual growth rate of 8.5% through the forecast period, according to a new analysis by Maximize Market Research.

North America leads treatment adoption on strong pharmaceutical research capabilities

North America holds the leading position in the market, supported by advanced healthcare infrastructure and higher awareness of autoimmune diseases. The United States drives regional demand through its established pharmaceutical industry and strong clinical research activity, while Canada contributes through its developed healthcare system focused on autoimmune disease management.

Holon, Israel – September 22, 2026 -- Compugen Ltd. (NASDAQ: CGEN) (TASE: CGEN) will host a virtual key opinion leader event on October 5, 2026 at 8:00 AM ET, presenting new detail on COM701, its anti-PVRIG antibody candidate for relapsed platinum-sensitive ovarian cancer (PSOC).

Harvard oncologist to preview MAIA-ovarian trial design and timeline

Oladapo Yeku, M.D., Ph.D., FACP, of Harvard Medical School and Massachusetts General Hospital, will join Compugen management to discuss the randomized MAIA-ovarian adaptive platform trial. The study evaluates COM701 as a maintenance therapy in relapsed PSOC patients, with median progression-free survival data from the interim analysis expected by Q1 2027. COM701 has already shown initial anti-tumor activity and a favorable safety and tolerability profile in Phase 1 studies as monotherapy and in combination regimens.

Shanghai – September 09, 2026 -- Harbour BioMed (HKEX: 02142.HK) shares became eligible for trading under the Shanghai-Hong Kong and Shenzhen-Hong Kong Stock Connect programs, opening direct access for qualified mainland Chinese investors effective immediately.

Market capitalization crosses HK$10 billion threshold

The inclusion follows the Company's market capitalization steadily surpassing HK$10 billion, placing it among large- and mid-cap biopharmaceutical issuers on the Hong Kong exchange.

First-half 2026 revenue rises 20.9% to $122.5 million

Harbour BioMed recorded total revenue of approximately US$122.5 million in the first half of 2026, up 20.9% year-over-year. Adjusted net profit reached approximately US$71.6 million, marking seven consecutive profitable half-years. Cash and cash equivalents stood at approximately US$359.2 million as of June 30, 2026.

SOUTH SAN FRANCISCO, Calif. -- September 01, 2026 -- IDEAYA Biosciences said its FDA Type C meeting on IDE849, a DLL3-targeting antibody drug conjugate, produced agreement on a Phase 3 registrational trial design for extensive stage small cell lung cancer (ES-SCLC). The Nasdaq-listed company (IDYA) plans to enroll roughly 400 patients who have already received tarlatamab, randomizing them 1:1 between IDE849 monotherapy and an investigator's choice control arm of topotecan and amrubicin. IDEAYA is targeting trial initiation by year-end 2026.