News

SHERIDAN, WYOMING – July 25, 2025 – Philips Foundation has announced the results of its 2024 activities in a newly published Annual Report, celebrating a milestone year that brought quality healthcare access to 46.5 million people globally—up from 28 million in 2023. The results mark a significant stride toward the Foundation’s 2030 goal of reaching 100 million underserved individuals each year.

Strategic Projects and Investments Drive Expansion

Throughout 2024, the Foundation initiated 22 new healthcare projects and five early-stage impact investments, with a strategic focus on primary care in underserved regions, particularly in India and Latin America. These initiatives leveraged Philips' health technology expertise to address rising non-communicable disease burdens and maternal health challenges.

SHERIDAN, WYOMING – July 25, 2025 – Royal Philips (NYSE: PHG, AEX: PHIA) has confirmed the exchange ratio for its 2024 dividend, announcing a share-based conversion rate of one new common share for every 23.6353 existing shares. The ratio was determined based on the volume-weighted average price of Philips shares traded on Euronext Amsterdam across May 30, June 2, and June 3, 2025, which stood at EUR 20.0600.

The final exchange ratio ensures that the gross value of the dividend in shares equates to approximately EUR 0.85, aligning with the company’s stated dividend target. As a result of this share-based payout, Philips will issue 22,980,748 new common shares.

Strategic Shareholder Participation and Dividend Structure

SHERIDAN, WYOMING – July 25, 2025 – Royal Philips has initiated a major international clinical trial to evaluate its new ultra-low X-ray dose technology designed for coronary procedures. The RADIQAL trial aims to generate real-world evidence that the innovation can significantly reduce radiation exposure for both patients and clinical staff without compromising the image quality or procedural performance critical to interventional cardiology.

Strategic push for radiation dose reduction in cardiology

As a global leader in health technology, Philips is targeting one of the central challenges in image-guided therapy: how to lower radiation exposure during procedures like percutaneous coronary intervention (PCI) while maintaining diagnostic confidence and procedural safety.

SHERIDAN, WYOMING – July 25, 2025 – In a significant move reshaping national vaccine policy, the U.S. Department of Health and Human Services (HHS) has announced it will eliminate thimerosal from all influenza vaccines distributed in the United States. The decision follows a unanimous vote by the Centers for Disease Control and Prevention’s Advisory Committee on Immunization Practices (ACIP) on June 26, 2025, and marks the end of an era for a preservative that has been both a practical necessity and a source of public debate for over two decades.

Strategic impact on manufacturers and supply chain

While thimerosal is currently used in only about 4% of flu vaccines—mainly multi-dose vials—the HHS ruling will require vaccine manufacturers to fully transition to thimerosal-free production. This includes replacing the final few thimerosal-containing products, namely two from Seqirus and one from Sanofi Pasteur, according to CDC data.

SHERIDAN, WYOMING – July 25, 2025 – Genentech, a member of the Roche Group, announced that the U.S. Food and Drug Administration (FDA) has issued a Complete Response Letter (CRL) for its supplemental Biologics License Application (sBLA) for Columvi® (glofitamab-gxbm) in combination with gemcitabine and oxaliplatin (GemOx). The application sought approval for this regimen as a second-line treatment for patients with relapsed or refractory diffuse large B-cell lymphoma (DLBCL) who are ineligible for autologous stem cell transplant.

FDA Response Highlights Evidence Requirements for Earlier-Line Indications

SHERIDAN, WYOMING – July 25, 2025 – Genentech has confirmed another round of workforce reductions at its South San Francisco headquarters, cutting 87 jobs effective September 15, 2025. The move comes as part of a broader, ongoing strategy to recalibrate operations and align resources with evolving scientific and business priorities.

This latest reduction, disclosed in a recent WARN Act notice, marks the second round of layoffs at the Roche subsidiary within two months. In June, Genentech had already parted ways with 143 employees at the same location. A company spokesperson had stated at the time, “Periodically, adjustments and decisions are necessary regarding the right makeup of our workforce within our company’s various functions,” emphasizing that the realignment is aimed at better meeting patient needs and advancing novel therapies.

Part of a Long-Term Realignment Strategy

SHERIDAN, WYOMING – July 25, 2025 – AbbVie and ADARx Pharmaceuticals have announced a major strategic collaboration and license option agreement to co-develop next-generation small interfering RNA (siRNA) therapeutics, targeting several high-impact disease areas including neuroscience, immunology and oncology.

The partnership combines ADARx’s proprietary siRNA platform with AbbVie's extensive biotherapeutic development and commercialization capabilities. siRNA molecules offer a novel modality to suppress disease-causing gene expression by silencing specific messenger RNA (mRNA) targets. This method bypasses traditional small molecule or antibody-based interventions by acting directly at the genetic message level.

Combining Complementary Strengths to Address Complex Diseases

SHERIDAN, WYOMING – July 25, 2025 – ADARx Pharmaceuticals is making waves in the RNA therapeutics landscape under the leadership of CEO Zhen Li, who has emerged as a key figure in advancing siRNA technologies with precision, partnership, and purpose. With a $200 million Series C financing round completed and a major strategic licensing deal secured with AbbVie, ADARx is expanding its pipeline while positioning itself for long-term commercial impact.

Forging a Leadership Path from Chemistry to Commercialization

SHERIDAN, WYOMING – July 25, 2025 – AstraZeneca has reported positive topline results from its Phase III PREVAIL trial evaluating gefurulimab, a complement C5-inhibiting nanobody, for the treatment of generalized myasthenia gravis (gMG). The investigational therapy met all primary and secondary endpoints, signaling a potential new contender in the highly competitive $20 billion gMG market.

Phase III Results Suggest Clinical Significance

According to AstraZeneca’s announcement, gefurulimab demonstrated “a statistically significant and clinically meaningful improvement from baseline” based on the Myasthenia Gravis Activities of Daily Living (MG-ADL) scale. Although specific trial data have not yet been published, the company confirmed that the results apply to patients with anti-acetylcholine receptor (AChR) antibody-positive gMG—representing approximately 85% of all gMG cases.

SHERIDAN, WYOMING – July 25, 2025 – Novartis AG has entered a strategic drug discovery alliance with Matchpoint Therapeutics, securing global rights to novel oral inhibitors aimed at treating multiple inflammatory conditions. The deal underscores Novartis' commitment to expanding its pipeline through innovation-driven partnerships and bolsters its focus on next-generation therapeutic platforms.

Strategic investment in covalent chemistry

The agreement grants Novartis full development and commercialization rights to molecules emerging from Matchpoint's proprietary discovery platform, known as the Advanced Covalent Exploration (ACE) platform. This cutting-edge technology identifies previously undruggable cryptic binding sites on disease-relevant proteins using covalent chemistry — a method that creates permanent bonds between drug and target.