Colorado Springs – September 17, 2026 -- Prime IV Hydration & Wellness has added Bioidentical Hormone Replacement Therapy (BHRT) and Niagen, a patented NAD+ precursor, to its service menu at select locations across its 215-plus site franchise network.
Prime IV expands physician-guided hormone therapy to address andropause and menopause symptoms
The BHRT program uses compounded bioidentical hormones delivered via a 100% USDA Certified Organic, solvent-free topical base designed for rapid absorption and minimized transfer risk. The offering includes initial consultation, personalized treatment planning, and ongoing provider access, targeting symptoms such as fatigue, mood changes, sleep disruption, brain fog, low libido, weight changes and decreased vitality. Prime IV has structured separate membership tracks for men and women to address andropause and perimenopause/menopause respectively.
Niagen therapy shifts NAD+ delivery model toward nicotinamide riboside precursor
Unlike direct NAD+ infusions, Niagen delivers nicotinamide riboside, a patented vitamin B3 form that the body converts into NAD+ through natural cellular pathways. Prime IV is offering Niagen across three formats -- IV infusions, injections and IV add-ons -- with shorter infusion times and compatibility with existing micronutrient protocols cited as operational advantages over standard NAD+ treatments.
Franchise network scales to 215 locations amid rising demand for personalized wellness services
Prime IV currently operates more than 215 locations nationwide, with over 315 franchises sold across 42 states. The company has ranked No. 1 in the IV Therapy category on Entrepreneur's Franchise 500 for three consecutive years, 2024 through 2026, and has appeared on the Inc. 5000 list in 2024, 2025 and 2026.
"With the addition of BHRT and Niagen, we're expanding the ways we can support our clients with more precision, more flexibility, and more innovative tools," said Amy Neary, Founder and CEO of Prime IV Hydration & Wellness.