SHERIDAN, WYOMING – July 29, 2025 – Sarepta Therapeutics is once again under regulatory spotlight following the death of an 8-year-old boy in Brazil who had received its gene therapy Elevidys, triggering an FDA investigation and fresh market turbulence for the embattled biotech.
SHERIDAN, WYOMING – July 29, 2025 – As the Alzheimer’s treatment market evolves beyond anti-amyloid antibodies, leading biopharma companies are doubling down on symptomatic therapies to address the daily struggles of patients and caregivers. While breakthrough drugs like Leqembi and Kisunla have changed the landscape with disease-modifying potential, their limitations are propelling renewed interest in managing Alzheimer’s-related psychosis, agitation, and cognitive decline—particularly in mid-to-late-stage patients.
SHERIDAN, WYOMING – July 29, 2025 – As the Alzheimer’s treatment landscape evolves beyond legacy amyloid-targeting approaches, five upcoming trial readouts are expected to deliver pivotal data that could shift both clinical practice and market leadership. From repurposed GLP-1 drugs to precision antibody therapies, leading pharma and biotech players are advancing differentiated strategies to address persistent unmet needs in Alzheimer’s care.
Data Milestones Poised to Shape the Post-Amyloid Era
SHERIDAN, WYOMING – July 29, 2025 – As Q2 earnings season ramps up, a diverse group of biotech leaders—ranging from Sarepta Therapeutics to Vertex Pharmaceuticals—find themselves navigating vastly different strategic terrain. From regulatory setbacks and gene therapy scrutiny to CRISPR approvals and pain therapy innovation, this quarter’s results could redefine investor confidence and reshape R&D roadmaps across the sector.
Sarepta Confronts Regulatory Turbulence and Gene Therapy Fallout
SHERIDAN, WYOMING – July 25, 2025 – Royal Philips has initiated a major international clinical trial to evaluate its new ultra-low X-ray dose technology designed for coronary procedures. The RADIQAL trial aims to generate real-world evidence that the innovation can significantly reduce radiation exposure for both patients and clinical staff without compromising the image quality or procedural performance critical to interventional cardiology.
Strategic push for radiation dose reduction in cardiology
SHERIDAN, WYOMING – July 25, 2025 – In a significant move reshaping national vaccine policy, the U.S. Department of Health and Human Services (HHS) has announced it will eliminate thimerosal from all influenza vaccines distributed in the United States. The decision follows a unanimous vote by the Centers for Disease Control and Prevention’s Advisory Committee on Immunization Practices (ACIP) on June 26, 2025, and marks the end of an era for a preservative that has been both a practical necessity and a source of public debate for over two decades.
SHERIDAN, WYOMING – July 25, 2025 – Genentech, a member of the Roche Group, announced that the U.S. Food and Drug Administration (FDA) has issued a Complete Response Letter (CRL) for its supplemental Biologics License Application (sBLA) for Columvi® (glofitamab-gxbm) in combination with gemcitabine and oxaliplatin (GemOx). The application sought approval for this regimen as a second-line treatment for patients with relapsed or refractory diffuse large B-cell lymphoma (DLBCL) who are ineligible for autologous stem cell transplant.
SHERIDAN, WYOMING – July 25, 2025 – Genentech has confirmed another round of workforce reductions at its South San Francisco headquarters, cutting 87 jobs effective September 15, 2025. The move comes as part of a broader, ongoing strategy to recalibrate operations and align resources with evolving scientific and business priorities.
SHERIDAN, WYOMING – July 25, 2025 – AbbVie and ADARx Pharmaceuticals have announced a major strategic collaboration and license option agreement to co-develop next-generation small interfering RNA (siRNA) therapeutics, targeting several high-impact disease areas including neuroscience, immunology and oncology.
SHERIDAN, WYOMING – July 25, 2025 – ADARx Pharmaceuticals is making waves in the RNA therapeutics landscape under the leadership of CEO Zhen Li, who has emerged as a key figure in advancing siRNA technologies with precision, partnership, and purpose. With a $200 million Series C financing round completed and a major strategic licensing deal secured with AbbVie, ADARx is expanding its pipeline while positioning itself for long-term commercial impact.
Forging a Leadership Path from Chemistry to Commercialization