Roche’s Trontinemab Shows Breakthrough Amyloid Clearance in Early Alzheimer’s Trial
SHERIDAN, WYOMING – July 29, 2025 – Roche has unveiled compelling early-stage data for its next-generation Alzheimer’s therapy, trontinemab, which demonstrated rapid and deep amyloid plaque clearance in patients after just seven months of treatment. The findings, presented at the 2025 Alzheimer’s Association International Conference in Toronto, suggest a potential leap beyond first-generation FDA-approved antibodies and set the stage for a new class of blood-brain barrier-penetrating biologics.