Healthcare, Pharma & Life Sciences

Cognixion Enrolls 30 ALS Patients in NIH-Funded BCI Trial

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Cognixion Enrolls 30 ALS Patients in NIH-Funded BCI Trial

Santa Barbara – November 04, 2026 -- Cognixion Corporation is enrolling 30 US adults with amyotrophic lateral sclerosis (ALS) in the CHOICE study, which tests its wearable brain-computer interface (BCI) against the eye-tracking speech devices patients use today. The trial is registered on ClinicalTrials.gov as NCT07871071 and is funded entirely by federal money from the National Institute on Deafness and Other Communication Disorders (NIDCD), part of the National Institutes of Health.

Participants test three communication options at home over 12 weeks

Each participant uses their own eye-tracking speech generating tablet, a head-worn Cognixion BCI with augmented reality display glasses, and a touchscreen-based version of the Cognixion system. Participants choose which option to use in each session. The time they voluntarily spend with each is the study's primary outcome measure.

German Study Tracks 1,000 Newborns; €2M Funds Forest Play Trial

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German Study Tracks 1,000 Newborns; €2M Funds Forest Play Trial

Bielefeld – November 04, 2026 -- Germany's federal research ministry is funding a sub-study worth roughly €2 million to test whether regular forest play changes children's risk of allergies, asthma and ADHD. The trial sits inside a long-term cohort of about 1,000 newborns in the East Westphalia-Lippe region.

The parent project, "Kleine Eulen OWL", is run by a research team at Evangelisches Klinikum Bethel (EvKB) at University Hospital OWL. The source describes it as unique nationwide. It follows the children into adulthood to map how the microbiome develops and how early living conditions affect later disease risk. Over the first six years of life, researchers analyze the influence of genes, pregnancy and birth, stress, environment, family, pets, lifestyle and medication on the microbiome.

Itemize Hires Ex-Wells Fargo Executive to Lead Healthcare Product

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Itemize Hires Ex-Wells Fargo Executive to Lead Healthcare Product

NEW YORK – November 04, 2026 -- Itemize, an AI Finance Operations provider, has appointed Doug Airulla, a healthcare payments veteran with more than 25 years of experience, as Product Manager for Healthcare Operations & Revenue Cycle.

Airulla will lead development of Itemize's healthcare solutions for providers, payers, Revenue Cycle Management (RCM) organizations and healthcare business process outsourcing companies. He will own the product roadmap and its commercialization.

Airulla brings Wells Fargo and J.P. Morgan treasury experience

Airulla joins from Wells Fargo, where he was Executive Director and Senior Product Solutions Specialist. There he advised healthcare organizations on revenue cycle and treasury management. He has helped close more than $60 million in revenue over his career.

CorroHealth CEO Pat Leonard Named CEO Magazine Executive of the Year

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CorroHealth CEO Pat Leonard Named CEO Magazine Executive of the Year

Plano, Texas – November 04, 2026 -- CorroHealth CEO Pat Leonard has been named to CEO Magazine's 2026 Executive of the Year Awards, after a nomination and evaluation process, the revenue cycle technology company said.

The magazine cited Leonard's strategic vision and operational discipline in building a foundation for accelerated growth. The awards recognize senior executives who drive business growth and transformation, champion innovation, build high-performing teams and navigate complex markets.

Leonard has led CorroHealth's operational transformation since 2020

Under Leonard, CorroHealth has combined clinician-led expertise with proprietary AI-driven technology. The company says the combination has made it a preferred partner in healthcare technology and revenue cycle management.

GrowthLoop, EVERSANA Take AI Decisioning to Biopharma Marketing

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GrowthLoop, EVERSANA Take AI Decisioning to Biopharma Marketing

New York – November 04, 2026 -- Morning email sends delivered a 13% higher weighted composite engagement score than afternoon sends in a biopharma campaign, contradicting existing predictive models, according to GrowthLoop and EVERSANA, which are expanding their Composable AI Decisioning solution into biopharmaceutical marketing.

The solution builds on GrowthLoop's composable customer data platform (CDP) and AI Studio. It uses continuous experimentation to identify which marketing actions lift healthcare professional (HCP) engagement, then feeds those findings into AI decisioning for subsequent interactions.

Genprex Links Low TROP2 to Reqorsa Resistance in Lung Cancer Models

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Genprex Links Low TROP2 to Reqorsa Resistance in Lung Cancer Models

Austin – November 04, 2026 -- Genprex, Inc. (NASDAQ: GNPX) reported that low TROP2 expression was consistently associated with primary resistance to its lead gene therapy Reqorsa (quaratusugene ozeplasmid) across multiple preclinical non-small cell lung cancer (NSCLC) models. The company says the finding could guide patient selection in future trials.

About half of tested NSCLC models showed primary resistance

Approximately 50% of 10 NSCLC cell lines and 50% of 12 patient-derived organoid models showed primary resistance to TUSC2 gene delivery. Protein-expression analyses identified low TROP2 expression as a marker associated with that resistance.

Patient biopsies from a TUSC2 trial back the association

Analysis of pretreatment tumor biopsies from patients enrolled in a TUSC2 gene therapy clinical trial supported the link between TROP2 expression and treatment response. The company did not disclose patient numbers or effect sizes.

Karyopharm Lands Two ASH 2026 Orals for Selinexor in Myelofibrosis

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Karyopharm Lands Two ASH 2026 Orals for Selinexor in Myelofibrosis

Newton, Mass. – November 04, 2026 -- Karyopharm Therapeutics (Nasdaq: KPTI) will present Week 48 data from its Phase 3 SENTRY trial and early monotherapy data from its Phase 2 SENTRY-2 trial in two oral sessions at ASH 2026, giving selinexor two oral slots in myelofibrosis. A third abstract, from the STOMP trial in multiple myeloma, was selected for a poster.

SENTRY Week 48 data go on stage December 13

The SENTRY presentation (publication number 526) is scheduled for December 13, 2026, from 10:15 a.m. to 10:30 a.m. CT. It will cover updated results for selinexor plus ruxolitinib in JAK inhibitor-naïve myelofibrosis. Chief Medical Officer Reshma Rangwala said the data show ongoing benefit through week 48.

Edgewise Posts $1.17B Q3 Profit on Servier Deal, Holds $1.74B Cash

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Edgewise Posts $1.17B Q3 Profit on Servier Deal, Holds $1.74B Cash

BOULDER, Colo. – November 04, 2026 -- Edgewise Therapeutics (Nasdaq: EWTX) reported third-quarter 2026 net income of $1,166.2 million, or $9.65 per diluted share, driven by a $1.348 billion gain on the sale of its sevasemten program and muscular dystrophy business to Servier. In the same period of 2025, the company posted a net loss of $40.7 million, or $0.39 per share.

Servier sale delivers $1.396 billion in upfront cash

The transaction closed in July 2026. Edgewise received $1.396 billion in upfront cash at closing. The reported gain includes consideration recognized at closing, among it amounts tied to the general indemnification arrangement. It is stated net of the carrying value of transferred assets, transaction costs and consideration allocated to transition services. Income tax expense associated with the transaction partly offset the gain in net income.

IM Cannabis Closes $1.2M Convertible Note With 15% Discount

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IM Cannabis Closes $1.2M Convertible Note With 15% Discount

Vancouver – November 04, 2026 -- IM Cannabis Corp. (Nasdaq: IMCC) has closed a US$1,200,000 convertible note financing with an existing institutional investor, issuing the note at an original issuance discount of 15% under a purchase agreement dated November 4, 2026.

Note carries 4% interest and a 28-month maturity

The note bears interest of 4% per annum, rising to 14% if an event of default occurs and continues. It matures 28 months after issuance and is repayable in 10 equal monthly instalments starting after the 18th month. The investor may convert all or part of the outstanding balance into common shares on one or more occasions.

Accuray Sets 1-for-40 Reverse Split to Regain Nasdaq Compliance

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Accuray Sets 1-for-40 Reverse Split to Regain Nasdaq Compliance

Madison, Wisconsin – November 04, 2026 -- Accuray Incorporated (NASDAQ: ARAY) will cut its outstanding common shares from about 120.2 million to about 3.0 million through a 1-for-40 reverse stock split effective at 12:02 a.m. Eastern Time on November 9, 2026. The move is intended to lift the per-share price and restore compliance with the minimum bid price requirement for The Nasdaq Capital Market.

Accuray begins split-adjusted trading on Nasdaq on November 9 under a new CUSIP

The company's board approved the split. Shares are expected to trade on a split-adjusted basis at the Nasdaq open on November 9 under the existing symbol "ARAY" and a new CUSIP number, 004397 303. Every 40 issued and outstanding shares will automatically combine into one share.